The pain-relieving mechanisms of spinal manipulation (hypoalgesia)

Neurophysiological Mechanisms of Spinal Manipulation-Induced Hypoalgesia

Spinal manipulation induces hypoalgesia, or a reduced sensitivity to pain, through a variety of complex neurophysiological mechanisms. These effects are thought to involve changes in the peripheral and central nervous systems, including spinal cord reflex pathways and descending pain modulation from the brain.